How To Cure Borderline Diabetes
How To Cure Borderline Diabetes – Can you reverse prediabetes? How to reverse prediabetes naturally? As an endocrinologist, I am often asked these questions.
Is there scientific evidence for this? We want evidence that prediabetes can be reversed in a significant population of people. In a landmark study called the Diabetes Prevention Program (DPP), a percentage of people reversed prediabetes through lifestyle changes or the diabetes drug, metformin.
How To Cure Borderline Diabetes
Prediabetes refers to blood sugar (plasma glucose) levels that are higher than normal, but do not meet the criteria for diabetes1. According to the American Diabetes Association (ADA), prediabetes is diagnosed with one of the following three criteria1:
Prediabetes Diagnosis And Treatment
The oral glucose tolerance test is one of the methods to detect prediabetes, diabetes mellitus and gestational diabetes. First, check your fasting glucose by taking blood. An individual drinks a drink with 75 grams of sugar. Check your glucose level by taking blood 1 and 2 hours after finishing the drink.
Prediabetes usually manifests itself without symptoms. Despite the lack of symptoms, prediabetes is associated with an increased risk of developing diabetes and cardiovascular diseases, such as heart disease.
Prediabetes can be unrecognized for years. Timely diagnosis and treatment are necessary to prevent the progression of diabetes and reduce the risk of cardiovascular diseases.
A 2006 study2 conducted at the Mayo Clinic examined 32 men and women with prediabetes and 28 men and women with normal blood sugar levels. Each person’s blood sugar and insulin levels were checked after a meal and with a 75-gram oral glucose tolerance test on separate occasions.
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As a group, blood sugar rose to higher levels in people with prediabetes compared to people with normal blood sugar levels. The higher blood sugar levels in people with prediabetes were due to a lower rate of blood sugar being taken up by the body’s cells. This simple illustration may help:
Glucose (blood sugar) filters out of the small blood vessels. Glucose must pass through the outer layer, called the cell membrane, into the inside of the cell. Insulin allows glucose to pass through the cell membrane into the cell. When the action of insulin is not efficient enough to allow glucose into the cell, glucose accumulates in the blood. In other words, higher blood sugar levels.
DPP3 was a clinical trial conducted at 27 centers across the United States from 1996 to 2001. The study included 3,234 people with prediabetes (but not diabetes).
For group 1, metformin was started at a dose of 850 mg per day. After 1 month, metformin was increased to 850 mg twice daily unless gastrointestinal side effects delayed the increase.
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The intensive lifestyle modification program includes a target weight loss of 7% of baseline body weight by following a low-calorie, low-fat diet and moderate-intensity physical activity, such as brisk walking, for at least 150 minutes per week. People in this group were given a curriculum of 16 lessons to achieve this goal.
Participants were followed for an average of 2.8 years. Let’s see the results by asking specific questions.
The estimated number of new cases of diabetes over a 3-year period was 28.9% in the placebo group, 21.7% in the metformin group, and 14.4% in the intensive lifestyle group.
Participants in the intensive lifestyle program group had their chances of developing type 2 diabetes reduced by 58% compared to the placebo.
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Participants in the metformin group had their chances of developing type 2 diabetes reduced by 31% compared to the placebo.
We define “reversed prediabetes” as normal fasting glucose and normal glucose at the 2-hour mark of the oral glucose tolerance test. The table below shows the percentage of participants in each group who achieved normal glucose according to both criteria, i.e. reversed prediabetes.
About 25% of participants in the placebo group reversed their prediabetes with standard lifestyle changes after 1 year. About 30% in the metformin group and over 40% in the intensive lifestyle group achieved a reduction in prediabetes.
We expect the number of participants who reverse prediabetes to decrease each year. The most interesting is the effectiveness of the intensive lifestyle group. About 30% of people in this group maintain normal blood sugar levels when extrapolated to 4 years.
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Metformin remained moderately more effective than placebo in maintaining normal blood glucose levels when assessed after 4 years.
We have evidence that prediabetes in the human population can be reversed by intensive lifestyle changes or metformin. Of those who did not reverse prediabetes, a significant number reduced their chances of developing type 2 diabetes.
Diagnosing prediabetes is the first step. Develop a personalized plan with your primary care physician or endocrinologist to reverse prediabetes or prevent progression to diabetes. Finally, it reduces the risk of cardiovascular diseases.
Schedule an initial consultation to discuss how we can create a customized plan for you. If you have comments or questions about prediabetes, please share them. in the comment section.
Prediabetes Subtypes Identified
Yes! The Diabetes Prevention Program has shown us that an intensive lifestyle program consisting of a low-calorie, low-fat diet and 150 minutes per week of moderate-intensity physical activity can reverse prediabetes (normalize blood sugar).
The most effective method, as shown by the Diabetes Prevention Program, is an intensive lifestyle program with a weight loss goal of 7% of the initial body weight. After 1 year, over 40% of participants in the intensive lifestyle group achieved normal fasting blood glucose and normal blood glucose at the 2-hour mark of the oral glucose tolerance test.
Prediabetes usually manifests itself without symptoms or warning signs. Despite the lack of symptoms and signs, prediabetes is associated with an increased risk of developing diabetes and cardiovascular diseases, such as heart disease.
Prediabetes can be unrecognized for years. Diagnosing prediabetes is the first step. Develop a personalized plan with your primary care physician or endocrinologist to potentially reverse prediabetes or prevent progression to diabetes. Figure 1: Drug-free diabetes remission data. Patients in the treatment group were assigned weight reduction through meal replacement, while control patients continued with medication and their standard diet. Patients in the weight loss category achieved 46% diabetes remission, compared to 4% in the usual care group.
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It is not easy and many will fail. However, people who managed to achieve remission were cured of one of the deadliest diseases and may have added years to their lives.
In fact, patients in the treatment group were removed from all previously prescribed diabetes and blood pressure medications.
It should be noted that the term remission is the medically preferred term for the reversal of diabetes, as diabetes always carries a risk of relapse. Even if you test negative for diabetes and stop taking all your medications, you would still be in remission.
For a chronic disease such as diabetes, it may be more accurate to use the term remission rather than cure. Current or potential future therapies for type 1 or type 2 diabetes are likely to always put patients at risk of relapse, due to underlying pathophysiological abnormalities and/or genetic predisposition.
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Figure 2: Data on diabetes remission and weight loss. People who lost more weight were more likely to achieve remission. Individuals who lost more than 33 pounds almost all achieved remission.
If we dig a little deeper into the data, we can see that your chances of remission depend on how much weight you lose.
Patients who lost more than 33 pounds almost all achieved remission. Patients who lost 11-22 pounds still did very well with a remission rate of 34%.
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Patients who lost no weight at all had a remission rate of 0%. This suggests that there was no magic in the formula or in the treatment. Without weight loss, diabetes is unlikely to go away on its own.
Patients assigned to the treatment group underwent 3-5 months of meal replacement where their meals were essentially replaced with protein shakes. They are then allowed to return to solid foods, with regular visits for nutrition counseling and weight loss.
This sounds unpleasant, but it is incredibly effective. Although the food replacement lasted only 3-5 months, it was enough to lead to a 46% remission 12 months after the start of the study.
These data show that it is really possible and feasible to get rid of diabetes without specialists and drugs.
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Our findings confirm that type 2 diabetes, which lasts up to 6 years, is not necessarily a permanent, lifelong condition. Weight loss sufficient to achieve remission can be achieved in many individuals with a structured, evidence-based weight management program delivered in a non-specialized community setting by routine primary care staff.
Given the simplicity of the treatment used, anyone should theoretically be able to replicate these results given enough time, consistency and dedication.
The patients were given meal replacement pills, which are a very effective way to lose weight. However, it is not the only way. Although not tested in this particular study, weight loss from a healthy diet should generally improve the symptoms and signs of diabetes.
Of course, if you have diabetes or are at risk, be sure to see your doctor. Untreated diabetes can be very harmful to your body and potentially
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